Difficulties or mistakes in diagnosing type 1 diabetes mellitus in children_ the consequences of delayed diagnosis (pdf download available)

of the study was to analyse difficulties in diagnosing T1DM and establish if delayed recognition is the main risk factor of diabetic ketoacidosis (DKA) in children with newly diagnosed T1DM.

Retrospective analysis of 335 children with new-onset T1DM, aged below 17 years and living in the Pomeranian region of Poland, was carried out. Type 1 diabetes mellitus definition The delay in diagnosis was recognized if the patient was not diagnosed on the first visit because of omission, wrong interpretation of symptoms, exclusive treatment of additional diabetic signs or concomitant diseases.

Difficulties in diagnosing T1DM were found in 54 cases (16.12%). Type 1 diabetes mellitus symptoms The initial diagnosis was wrongly categorized as respiratory system infection (46.3%), perineal candidiasis (16.6%), gastroenteritis (16.6%), urinary tract infection (11.1%), stomatitis (11.1%), appendicitis (3.7%). Definition of type 1 diabetes Duration of symptoms (mean 14 days) and glycated haemoglobin level did not significantly correspond with diagnostic delay. Late onset type 1 diabetes symptoms DKA was significantly more frequent in children with delayed diagnosis – 33 patients (61.11%) (p=0.0005). Reversing type 1 diabetes naturally The infection preceding diagnosis of T1DM, more common among children with delayed recognition, did not affect the duration of symptoms or affect characteristicly more frequent DKA development in children with diagnostic delay.

No significant associations between diagnostic delay and duration of diabetic symptoms as well as glycated haemoglobin level exclude possibility of delayed diagnosis because of slow development of diabetic symptoms.

Signs of type 1 diabetes in child Significantly more frequent DKA development in children with delayed recognition, irrespective of infection preceding diagnosis, and no confirmation that younger patient’s age predisposes to quick increase of DKA point out that the main risk factor for DKA development in the research group was diagnostic delay.

[Show abstract] [Hide abstract] ABSTRACT: The diagnostic criteria needed to differentiate between type 1 and type 2 diabetes seemed clear not so long ago. Type 1 diabetes in babies It was believed that just as the insulin deficit connected with β-cell destruction was typical of type 1 diabetes, the insulin resistance was a specific feature of type 2 diabetes. Type 1 diabetes statistics At present it is known that hyperglycaemia originates from these both disorders. Juvenile onset diabetes The differences are quantitative, rather than qualitative. Difference between type1 and type 2 diabetes symptoms Moreover, the background mechanism and the increase rate of each these phenomena can also be different which gives specific clinical picture. Difference between type1 and type 2 diabetes The growing availability of excellent diagnostic measures have led to a notion that this old classification is not enough. Type 1 diabetes autoimmune disease The increasing number of cases which cannot be unambiguously classified according to the still valid WHO criteria from 1998 creates strong necessity to revise and set up a new division. Type 1 diabetes ppt These difficulties concern mainly children, adolescents and young adults. Type 1 diabetes in toddlers Is there a type 1,5 diabetes then? A constant progress in the field of genetics and immunology allows us to broaden the studies of diabetes pathogenesis and patophysiology. Type 1 diabetes life expectancy 2015 In the light of new evidence formerly described characteristics of types of diabetes loose their specificity and tend to permeate through one another. Cure type 1 diabetes naturally One should also keep in mind some other certain types of diabetes that can be encountered. Diabetes type 1 life expectancy The whole group of monogenic types of diabetes, which are more and more frequently diagnosed, form a good example. Type 1 diabetes autoimmune The growing body of evidence contributes to a great need to revise and verify the old diagnostic criteria for diabetes.