Patent us20110052655 – methods and vesicles for controlling protozoa – google patenten

8. How to cure trichomoniasis The method of claim 6 wherein the biocide is chosen from the group consisting of guanidine or biguanidine salts, quaternary ammonium salts, phosphonium salts, 2-bromo-2-nitropropane-1,3-diol, 5-chloro-2-methyl-4-isothiazolin-3-one/2-methyl-4-isothiazolin-3-one, n-alkyl-dimethylbenzylammonium chloride, 2,2, dibromo-3-nitrilopropionamidemethylene-bis(thiocyanate), dodecylguanidine hydrochloride, glutaraldehyde, 2-(tert-butylamino)-4-chloro-6-(ethylamino)-s-triazine, beta-bromonitrostyrene, tributyltinoxide, n-tributyltetradecyl phosphonium chloride, tetrahydroxymethyl phosphonium chloride, 4,5,-dichloro-1,2,-dithiol-3-one, sodium dimethyldithiocarbamate, disodium ethylenebisdithiocarbamate, Bis(trichloromethyl) sulfone, 3,5-dimethyl-tetrahydro-2H-1,3,5,-thiadiazine-2-thione, 1,2,-benzisothiazolin-3-one, decylthioethylamine hydrochloride, copper sulfate, silver nitrate, bromochlorodimethylhydantoin, sodium bromide, dichlorodimethylhydantoin, sodium hypochlorite, hydrogen peroxide, chlorine dioxide, sodium chlorite, bromine chloride, peracetic acid and precursors, sodium trichloroisocyanurate, sodium trichloroisocyanurate, dibromo, dicyano butane and combinations thereof.

19. What is trichomoniasis std The method of claim 18 wherein the biocide is chosen from the group consisting of guanidine or biguanidine salts, quaternary ammonium salts, phosphonium salts, 2-bromo-2-nitropropane-1,3-diol, 5-chloro-2-methyl-4-isothiazolin-3-one/2-methyl-4-n-alkyl-dimethylbenzylammonium chloride, 2,2, dibromo-3-nitrilopropionamidemethylene-bis(thiocyanate), dodecylguanidine hydrochloride, glutaraldehyde, 2-(tert-butylamino)-4-chloro-6-(ethylamino)-s-triazine, beta-bromonitrostyrene, tributyltinoxide, n-tributyltetradecyl phosphonium chloride, tetrahydroxymethyl phosphonium chloride, 4,5,-dichloro-1,2,-dithiol-3-one, sodium dimethyldithiocarbamate, disodium ethylenebisdithiocarbamate, Bis(trichloromethyl) sulfone, 3,5-dimethyl-tetrahydro-2H-1,3,5,-thiadiazine-2-thione, 1,2,-benzisothiazolin-3-one, decylthioethylamine hydrochloride, copper sulfate, silver nitrate, bromochlorodimethylhydantoin, sodium bromide, dichlorodimethylhydantoin, sodium hypochlorite, hydrogen peroxide, chlorine dioxide, sodium chlorite, bromine chloride, peracetic acid and precursors, sodium trichloroisocyanurate, sodium trichloroisocyanurate, dibromo, dicyano butane and combinations thereof.

28. Images of trichomoniasis The vesicle of claim 26 wherein the biocide is chosen from the group consisting of guanidine or biguanidine salts, quaternary ammonium salts, phosphonium salts, 2-bromo-2-nitropropane-1,3-diol, 5-chloro-2-methyl-4-isothiazolin-3-one/2-methyl-4-isothiazolin-3-one, n-alkyl-dimethylbenzylammonium chloride, 2,2, dibromo-3-nitrilopropionamidemethylene-bis(thiocyanate), dodecylguanidine hydrochloride, glutaraldehyde, 2-(tert-butylamino)-4-chloro-6-(ethylamino)-s-triazine, beta-bromonitrostyrene, tributyltinoxide, n-tributyltetradecyl phosphonium chloride, tetrahydroxymethyl phosphonium chloride, 4,5,-dichloro-1,2,-dithiol-3-one, sodium dimethyl dithiocarbamate, disodium ethylenebisdithiocarbamate, Bis(trichloromethyl) sulfone, 3,5-dimethyl-tetrahydro-2H-1,3,5,-thiadiazine-2-thione, 1,2,-benzisothiazolin-3-one, decylthioethylamine hydrochloride, copper sulfate, silver nitrate, bromochlorodimethylhydantoin, sodium bromide, dichlorodimethylhydantoin, sodium hypochlorite, hydrogen peroxide, chlorine dioxide, sodium chlorite, bromine chloride, peracetic acid and precursors, sodium trichloroisocyanurate, sodium trichloroisocyanurate, dibromo, dicyano butane and combinations thereof.


Aqueous systems, such as water distribution systems, cooling towers, showers, aquaria, sprinklers, spas or cleaning baths, can contain protozoa and some types of protozoa can be harmful, causing pathogenic protozoa infections, such as amoebic dysentery, malaria, Giardiasis, Trichomoniasis or Cryptosporidiosis. Trichomoniasis long term effects Other types of protozoa can harbor harmful bacteria that live within the protozoa, grow symbiotically or parasitically within the host cells, and not be killed or inhibited by the host cell. Metronidazole for trichomoniasis These parasites have developed ways of interacting and overcoming the host cells natural defense mechanisms. What is trichomonas infection Legionella pneumophila, a bacterium known to cause Legionnaire’s Disease and Pontiac fever in humans is a parasite of this type. Trichomonas vaginalis life cycle Two protozoa species capable of harboring infectious Legionella are Acanthamoeba and Tetrahymena.

Protozoa are natural grazers on surfaces and engulf and digest bacteria as part of their natural life cycle. Can you have trichomonas for years and not know it Legionella are often found in biofilms adsorbed to solid surfaces in aqueous systems. How can you get trichomoniasis In most cases, the protozoa digest these bacteria through the use of digestive enzymes in their phagosomes (digestive vacuoles). How to get rid of trichomoniasis In the case of Legionella, however, this is not the case. Male trichomoniasis The protozoa are not readily capable of degrading the engulfed Legionella cells, and in fact, the Legionella grow and increase their numbers while protected within protozoa phagosomes. Trichomoniasis symptoms female Legionellosis in humans can be contracted by breathing Legionella aerosols containing either the free-living bacterial cells or by inhaling aerosols of Legionella concentrated within susceptible protozoa. Trichomoniasis symptoms come and go Pathogens, such as Legionella cells, and protozoa can be killed with certain chemical agents and antibiotics. Trichomonas vaginalis images However, some protozoa, particularly amoeboid forms, have evolved mechanisms for surviving in hostile environments. Whats trichomoniasis Examples of hostile environments are high temperature, desiccation, presence of chemical agents/antibiotics, lack of food sources, etc. Trichomoniasis symptoms in males Upon encountering a hostile environment, these protozoa revert to a cyst form that is very difficult to kill or contain. Trichomonas vaginalis pdf The cyst form becomes much less susceptible to chemical agents that readily kill the same organism when it is in non-cyst (trophozoite) form. Symptoms for trichomoniasis Introduction of a chemical control agent to eliminate these types of protozoa, such as Acanthamoeba or Tetrahymena, can trigger the protozoa to revert to a cyst form, thereby rendering it invulnerable to the chemical agent. What is trichomoniasis caused by When the cyst contains the pathogen Legionella, the chemical agent can no longer reach the engulfed bacteria, and the chemical treatment is rendered ineffective.

Currently, there are no known cyst deactivating agents in commercial use at this time. Trichomoniasis discharge pictures Although control agents, which can kill or treat the Legionella bacteria are known, there is no method currently in use which provides for the means to effectively introduce control agents into the aqueous systems where the Legionella bacteria and Legionella harboring protozoa reside. Trichomoniasis in women Control agents that control the Legionella harboring protozoa and protozoan cysts provide a much needed additional tool to safeguard the health of workers and the public against the respiratory pneumonias which can result from inhalation of Legionella or Legionella-containing protozoa cysts.

Approximating language, as used herein throughout the specification and claims, may be applied to modify any quantitative representation that could permissibly vary without resulting in a change in the basic function to which it is related. Signs of trichomoniasis Accordingly, a value modified by a term or terms, such as “about”, is not limited to the precise value specified. What is trichomonas vaginalis In at least some instances, the approximating language may correspond to the precision of an instrument for measuring the value. How can you catch trichomoniasis Range limitations may be combined and/or interchanged, and such ranges are identified and include all the sub-ranges included herein unless context or language indicates otherwise. Trichomoniasis cdc Other than in the operating examples or where otherwise indicated, all numbers or expressions referring to quantities of ingredients, reaction conditions and the like, used in the specification and the claims, are to be understood as modified in all instances by the term “about”.

The protozoa to be controlled may be any type of protozoa within an aqueous system. Trichomonas vaginalis treatment In one embodiment, the protozoa may be in its trophozoite form or cyst form. Symptoms of trichomoniasis in males In one embodiment, the protozoa trophozoite or cyst contains a pathogen, which has been engulfed by the phagosome in the protozoa vacuole. Symptoms trichomoniasis In another embodiment, the protozoa contains Legionella pneumophila. Trichomoniasis symptoms in men In another embodiment, the protozoa may be Acanthamoeba or Tetrahymena. What are the symptoms of trichomoniasis in males In an alternate embodiment, the protozoa may be infection carrying protozoa including, but not limited to, those that result in amoebic dysentery, malaria, Giardiasis, Trichomoniasis, Cryptosporidiosis and other pathogenic protozoa.

The micro-capsule or nano-capsule is a microscopic vesicle or type of structure that encloses a biocide or non-biocidal agent and is for delivering the biocide or non-biocidal agent to the protozoa trophozoites or cysts in an aqueous system. How to treat trichomoniasis In one embodiment, the micro-capsule or nano-capsule contains the biocide or non-biocidal agent within its core. How is trichomoniasis treated The micro-capsule or nano-capsule may be produced by any known process and has a similar composition of a microbial membrane and size of a microbial cell and is produced such that it has an exterior composition adapted for digestion by the protozoa. Trichomoniasis images In one embodiment, the micro-capsule or nano-capsule may be prepared from material, such as lecithin, gums, gels, biodegradable or non-biodegradable polymers, such as polylactic acid or polystyrene, organic polymers, combinations of lecithin and organically functionalized lecithin where the functionalization can either be polymer chains, peptides, proteins, lipids, cholesterols or bio receptors. Can trichomoniasis come back The material may also be multi-block polymers containing hydrophobic and hydrophilic blocks, self-assembled Donor:Acceptor moieties and micelles, inorganic spheres, rods, cages or particles.

The active protozoa, the trophozoite stage, grazes on the micro-capsules or nano-capsules, mistaking them for bacteria cells. Signs and symptoms of trichomoniasis Once engulfed or phagocitized by the protozoa, the natural enzymatic breakdown of the biocide- or non-biocidal agent-containing micro-capsule or nano-capsule by the protozoa would result in the release of the biocide or non-biocidal agent in high concentration in the protozoa. Can trichomoniasis be cured If the protozoa contained engulfed pathogens, such as Legionella, the release of the biocide or non-biocidal agent would be in direct proximity to the engulfed pathogen and rapid death of the pathogen, such as Legionella, would then proceed. Sti trichomoniasis This method would also inactivate the host protozoa by the biocide or non-biocidal agent, such as by destroying it or preventing it from spreading or reproducing. Is trichomoniasis an std In the event that the protozoa are already in the cyst stage, the addition of micro-capsules or nano-capsules prepared with bacterial cell size and suitable membrane characteristics would induce the cysts to excyst or revert to active trophozoite stage in order to take advantage of the new food source. How is trichomoniasis tested At that point, grazing and engulfing of the micro-capsules or nano-capsules by the protozoa would then occur.

The biocide may be any type of biocide that is suitable for killing or destroying the protozoa and any engulfed pathogens. Causes of trichomoniasis In one embodiment, the biocide may be a non-oxidizing, oxidizing or molluscicide antimicrobial compounds, or combinations thereof. How do you test for trichomoniasis In another embodiment, the biocide includes, but is not limited to, guanidine or biguanidine salts, quaternary ammonium salts, phosphonium salts, 2-bromo-2-nitropropane-1,3-diol, 5-chloro-2-methyl-4-isothiazolin-3-one/2-methyl-4-isothiazolin-3-one, n-alkyl-dimethylbenzylammonium chloride, 2,2, dibromo-3-nitrilopropionamidemethylene-bis(thiocyanate), dodecylguanidine hydrochloride, glutaraldehyde, 2-(tert-butylamino)-4-chloro-6-(ethylamino)-s-triazine, beta-bromonitrostyrene, tributyltinoxide n-tributyltetradecyl phosphonium chloride, tetrahydroxymethyl phosphonium chloride, 4,5,-dichloro-1,2,-dithiol-3-one, sodium dimethyldithiocarbamate, disodium ethylenebisdithiocarbamate, Bis(trichloromethyl) sulfone, 3,5-dimethyl-tetrahydro-2H-1,3,5,-thiadiazine-2-thione, 1,2,-benzisothiazolin-3-one, decylthioethylamine hydrochloride, copper sulfate, silver nitrate, bromochlorodimethylhydantoin, sodium bromide, dichlorodimethylhydantoin, sodium hypochlorite, hydrogen peroxide, chlorine dioxide, sodium chlorite, bromine chloride, peracetic acid and precursors, sodium trichloroisocyanurate, sodium trichloroisocyanurate, dibromo, dicyano butane and combinations thereof.

The non-biocidal agents may be any type of environmentally friendly compound or composition that removes or inactivates the protozoa to keep it from spreading, such as by interfering with its life or reproductive cycle. Trichomoniasis sores In one embodiment, the non-biocidal agent may be used as an adjuvant with a biocide. Std trichomoniasis For example, non-biocidal agents include, but are not limited to, biodispersants, ethylene oxide/propylene oxide copolymers, trichlorohexanoic acid, polysiloxanes, carbosilanes, polyethyleneimine, bacteria, microorganisms, plasmids, phagocytes, macrophages, toxin-producing microorganisms, amino acids, proteins, peptides, DNA, RNA, base pairs, antisense RNA pharmaceuticals, antibiotics, chelators, natural extracts, organic/inorganic redox agents, organic and inorganic dye sensitizers, apoptosis signaling reagent, microorganism- and plant-derived extracts and by-products, metabolic components, preservatives, toxic phytochemicals, microbial toxins, catalysts that generate free radicals or active oxygen species, L-cystin and enzymes or combinations thereof.

The liposomes may be the encapsulating bodies containing the biocide or non-biocidal agent, or such a biocide- or non-biocidal agent-containing liposomes may themselves be further encapsulated, e.g., by a thin shell of protective material. Trichomoniasis pics In the latter case, the shell may, for example, be compounded to provide a further, temporary protective cover for the liposome, such as a degradable skin, that enhances the lifetime of the liposome in the water system yet dissolves, decays or otherwise breaks down after a certain time, or under certain conditions, releasing the liposomes which may then act on the target organisms.

The vesicles may be added in an aqueous system to control protozoa, such as by reducing, removing or inactivating the protozoa and contain the protozoa from spreading. Trichomonas infection The protozoa types and its stages are described above. Symptoms of trichomonas infection A biocide or non-biocidal agent for controlling the protozoa is encapsulated into a vesicle. How do you treat trichomoniasis The vesicle contains an exterior composition or material adapted for digestion by the protozoa and a shape to mimic bacteria on which the protozoa feeds. What are the symptoms of trichomoniasis The protozoa are tricked into feeding on the vesicle and engulfing it. Is trichomoniasis a bacterial infection As the vesicle is digested, the biocide or non-biocidal agent is released to act on the protozoa. Trichomoniasis symptoms men When the protozoa contains pathogens, such as Legionella, the engulfed biocide or non-biocidal agent can act on the protozoa as well as the pathogen inside the protozoa. Symptoms of trichomoniasis The vesicle does not cause the protozoa trophozoite to revert to a cyst stage, as it appears benign to the protozoa. How do u get trichomoniasis Also, any protozoa in cyst form are induced into an active trophozoite form in order to feed on the vesicles.