Screening could prevent one in five ovarian cancer deaths, study shows – telegraph

More than 7,000 women are diagnosed with ovarian cancer each year and more than 4,000 will die from the disease, most because it was picked up too late for treatments to be effective.

To find out if screening could be effective researchers launched the UK Collaborative Trial of Ovarian Cancer Screening in 2001 and recruited 200,000 women between 50 to 74. Cancer blood clots A quarter were offered a a blood test which looks for the protein CA125, while another 50,000 were offered an ultrasound check. Prostate cancer blood in urine The remaining 100,000 were kept as a control group.

Over that period far more women died from ovarian cancer in the control group than in the group that was checked each year.


Cancer and blood specialists of nevada The results suggest that spotting the disease early could prevent the deaths of 20 per cent of women who develop the disease. Symptoms of blood cancer in hindi It means that if the tests were rolled out across Britain, nearly 1,000 deaths could be prevented each year.

Study author Professor Ian Jacobs who developed the blood test in 1996, said: “I am delighted that the results suggest that early detection by screening can save lives.

“Longer follow up is needed but this brings hope in the fight against a disease for which the outlook for women is poor and has not improved much during the last three decades.”

Prof Christina Fotopoulou, an ovarian cancer surgeon from the Ovarian Cancer Action Research Centre, said “We’ve always been one step behind the disease but a screening method would allow us to catch it at a stage that makes treatment more effective.”

However the study did show that for every three women who had surgery to check for ovarian cancer – based on their blood test results – two did not have any disease. Blood cancer reasons Not only does this lead to needless worry for women, but could place added strain on NHS budgets. Causes of blood cancer in hindi And three per cent of women who had surgery needlessly ended up with major complications. Cancer and white blood cell count Cancer Research UK who helped fund the study said it would amount to ‘a lot of unnecessary surgery.’

Dr Fiona Reddington, Cancer Research UK’s head of population research, said: “This trial has been incredibly useful in improving our understanding of ovarian cancer.

Athena Lamnisos, CEO of The Eve Appeal said: “These results don’t necessarily signal the introduction of a national screening programme, but they are an exciting step forward for early detection of ovarian cancer.

Dr Clare Mckenzie, consultant gynaecological oncologist and Vice President for the Royal College of Obstetricians and Gynaecologists (RCOG) said the findings were promising.

“However, longer follow up is needed to determine how effective the test is. Blood cancer diagnosis Women who are worried about ovarian cancer should talk to their doctor who can explain their risk of cancer and available tests.”

Dr Adam Shaw, Clinical Lead for Cancer Genetics, Guy’s & St Thomas’ NHS Foundation Trust, added “The potential this study shows for earlier detection of ovarian cancer and the number of lives saved is very encouraging.”